We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
Chinese Journal of Dental Research
Chin J Dent Res 22 (2019), No. 1     28. Feb. 2019
Chin J Dent Res 22 (2019), No. 1  (28.02.2019)

Page 57-64, doi:10.3290/j.cjdr.a41776, PubMed:30746534


Evaluation of Paste Containing Gentamicin, Amoxicillin and Metronidazole in Endodontic Treatment of Primary Molars in Vivo
Parakh, Keyura / Shetty, Raghavendra Manjunath
Objective: To evaluate and compare the efficacy of gentamicin, amoxicillin and metronidazole (GAM) antibiotic paste in noninstrumentation and instrumentation techniques in infected primary molars.
Methods: Sixty primary molars in children of 4 to 8 years were selected and divided into four groups: teeth without any periapical or furcation involvement undergoing pulpectomy by noninstrumentation (Group N1) and instrumentation (Group N2) technique using GAM antibiotic paste; teeth with periapical or furcation involvement undergoing pulpectomy by noninstrumentation (Group R1) and instrumentation (Group R2) technique using GAM antibiotic paste. Regular follow-up at 3, 6 and 12 months was carried out for each group and all the clinical and radiographic changes were evaluated statistically using SPSS software. The level of significance was set to P < 0.05.
Results: Overall, 73.3% of success was observed in Group N1, 71.4% in Group N2, 86.7% in both Group R1 and Group R2 (P = 0.003).
Conclusion: The GAM lesion sterilisation and tissue repair (GAM-LSTR) technique can be an alternative to conventional pulpectomy.

Keywords: antibiotic paste, primary molars, pulpectomy, gentamicin, amoxicillin, metronidazole