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Chinese Journal of Dental Research
Chin J Dent Res 21 (2018), No. 2     28. June 2018
Chin J Dent Res 21 (2018), No. 2  (28.06.2018)

Page 135-141, doi:10.3290/j.cjdr.a40440, PubMed:29808177

Discrepancy of Clinical Parameters between the First and Second Molars Can Help to Differentiate Subjects with Aggressive Periodontitis from Chronic Periodontitis: a Cross-sectional Study Based on a Large Chinese Population
Jiao, Jian / Zhao, Jing Ren / Zhang, Li / Shi, Dong / Lu, Rui Fang / Meng, Huan Xin
Objective: To explore associations between mean discrepancy values for the first and second molars (MDVFSs) and generalised aggressive periodontitis (GAgP) using hospital-based periodontal examination records from a large Chinese population.
Methods: Data from consecutive patients diagnosed as having chronic periodontitis (CP, n = 51,849) and GAgP (n = 2,706) were included. Patient ages, gender, smoking status, mean full-mouth probing depth (PD), and mean full-mouth attachment loss (AL), as well as MDVFSs for PD and AL, were extracted. Multivariate linear regression was used to test associations between MDVFSs and GAgP.
Results: After multivariate risk adjustment for potential confounding factors (age, smoking status, and mean PD and AL), the MDVFSs for PD (OR = 2.20, 95%CI: 2.04 to 2.38, P < 0.001) and AL (OR = 1.51, 95CI%: 1.44 to 1.59, P < 0.001) were significantly associated with GAgP. The probability of GAgP was associated with MDVFS for PD falling between 0 mm and 2.5 mm (OR = 4.55, 95%CI: 4.01 to 5.17) and MDVFS for AL falling between 0 mm and 3.5 mm (OR = 2.01, 95%CI: 1.86 to 2.16, P < 0.001).
Conclusion: This study revealed associations between MDVFSs and GAgP, demonstrating that MDVFSs can serve as promising auxiliary references for the differential diagnosis between CP and GAgP.

Keywords: aggressive periodontitis, chronic periodontitis, diagnosis