We are using cookies to implement functions like login, shopping cart or language selection for this website and to create anonymized statistical reports of the usage. You will find more information in our privacy policy. By continuing to use our website, you agree to this. Yes, I agree
Chinese Journal of Dental Research
Chin J Dent Res 19 (2016), No. 4     19. Dec. 2016
Chin J Dent Res 19 (2016), No. 4  (19.12.2016)

Page 231-237, doi:10.3290/j.cjdr.a37148, PubMed:27995228


A Novel Approach Using 15% Natural Chitosan Gel in the Management of Intrabony Defects: A Pilot Study
Babrawala, Irfana / Munivenkatappa Lakshmaiah Venkatesh, Prabhuji / Bangalore Varadhan, Karthikeyan
Objective: To evaluate the effectiveness of 15% chitosan in gel form as a periodontal regenerative material in the periodontal intrabony defects.
Methods: A pilot study split-mouth design of 10 patients within the age group of 30 to 55 years with bilateral intrabony defects ? 3mm and clinical attachment levels (CAL) ? 5mm were selected. The test site received open flap debridement with 15% Chitosan gel as a regenerative material and the controlateral side that acted as a control received only open flap debridement. Clinical and radiographic measurements were recorded at baseline, and 3, 6 and 9 months after the treatment.
Results: Data revealed that there was a significant improvement in both clinical and radiographic parameters when intragroup comparison was performed. When intergroup comparison was done, there was a mean difference in CAL (5.8 ± 1.398 mm) and the depth of the intrabony defect (3.41 ± 1.17 mm) at 9 months when compared to baseline.
Conclusion: Within the limitations of the study, it can be concluded that a 15% concentration of chitosan gel is a promising aid and could be used as an effective material in periodontal regeneration.

Keywords: bone graft, chitosan, periodontal regeneration, wound healing